Sharing my experience. Below is my post in the PMS50 discord un Jun 29, 2025:
Repeatable MSFS2020 CTD when PMS GTN750/650 is used. A/C is BlackSquare Duke.
I've been testing this all morning, and can consistently and repeatably cause a CTD at the exact same position only when using the GTN750/650.
I have NOTHING in my community folder other than the Blacksquare Duke and the PMS50 GTN750.
When I try the exact route with the default DA62, no issues.
When I try the exact route with the Blacksquare Duke and GNS530/430, no issues.
When I try the exact route with the Blacksquare Duke and PMS50 GTN750, I get a CTD. I did this 4x times, and the CTD repeats consistently. I downloaded and installed the latest version 2.2.48 of the GTN750. Still CTD.
If I don't use the GTN750, it does not CTD.
I've read many post stating that PMS50 GTN750 cannot cause a CTD. I don't know what to say, but that's not my experience.
Here's the flight plan. Cruise altitude is 13,000. Departure time about 10am local. KBTV DCT OMPEE DCT SQUAM DCT LIMER DCT KPWM
The CTD occurs about halfway between OMPEE and SQUAM.
Update:
I still had version 2.2.36 on my PC. I had flown ~60 hrs with this version in the BlackSquare Duke without a single CTD, so I reverted to 2.2.36, and tried the problem flight plan. No CTD. So, I'm back to using 2.2.36 indefinitely. That's fine with me. Also, during my testing I had absolutely nothing else running at all, and it still CTDed. I didn't have any third party apps running.